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Microcosm is a QuickTime codec targeted at lossless encoding of 64BPP RGBA movies. This codec was designed as an editing format and doesn't seem to be used for media distribution. Digital Anarchy offers a demo version for Mac and Windows that watermarks the video data, but doesn't seem to have time expiration.

They also developed a freeware uncmpressed codec for 64BPP RGBA movies called None16.

Looks like this codec uses range coding, optional RLE and fixed or adaptive prediction — all operations are performed on bytes or shorts, depending on codec bitdepth.